[HTML][HTML] Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation
A Arici, I Sozen - Fertility and sterility, 2000 - Elsevier
Objective: To investigate the expression of TGF-β3 in leiomyoma and myometrium as well as
the effect of TGF-β3 on the expression of fibronectin and on the proliferation of leiomyoma
and myometrial cells. Design: Observational and in vitro experimental study. Setting:
University medical center. Patient (s): Women with (n= 18) leiomyoma. Intervention (s): First
TGF-β3 mRNA and protein levels in myometrium and leiomyoma were measured, and then
myometrial and leiomyoma cells in culture were treated with TGF-β3. Main Outcome …
the effect of TGF-β3 on the expression of fibronectin and on the proliferation of leiomyoma
and myometrial cells. Design: Observational and in vitro experimental study. Setting:
University medical center. Patient (s): Women with (n= 18) leiomyoma. Intervention (s): First
TGF-β3 mRNA and protein levels in myometrium and leiomyoma were measured, and then
myometrial and leiomyoma cells in culture were treated with TGF-β3. Main Outcome …
